Prevalence and its associated risk factors for oral lichen planus in Central Indian population
DOI:
https://doi.org/10.48165/ajm.2026.9.01.44Keywords:
Oral lichen planus, prevalence, risk factors, Central India, tobacco, diabetes mellitusAbstract
Background: Oral lichen planus is a chronic immune-mediated mucosal disorder that may present with white striations, erythematous areas, erosions or ulcerations. It is clinically important because it can cause burning sensation, discomfort during eating and, in some cases, requires long-term surveillance due to its potentially malignant nature. Aim: The study aimed to assess the prevalence of oral lichen planus and its associated risk factors among the Central Indian population attending outreach programmes conducted by People’s College of Dental Sciences and Research Centre, Bhopal. Methodology: A community-based cross-sectional study was conducted among 2000 patients screened during institutional outreach oral health programmes. Demographic details, tobacco habits, systemic history, perceived stress, oral hygiene status and local dental irritants were recorded using a predesigned proforma. Oral examination was carried out under adequate illumination, and clinically suspected cases of oral lichen planus were identified based on characteristic oral features. A biopsy was advised for erosive, atypical, or doubtful lesions. Data were analysed using descriptive statistics, chi-square test and multivariable logistic regression. Results: Oral lichen planus was diagnosed in 44 patients, giving an overall prevalence of 2.2%. The condition was more common among females and among patients aged 40 and above. Reticular oral lichen planus was the most frequent clinical type, and buccal mucosa was the most commonly affected site. Significant associated factors included tobacco use, high perceived stress, diabetes mellitus, local dental irritation and poor oral hygiene. Conclusion: Oral lichen planus showed a prevalence of 2.2% in the screened Central Indian population. Community-based screening may help with early detection, risk factor identification, counselling, and timely referral for follow-up.
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References
Gupta S, Jawanda MK. Oral lichen planus: An update on etiology, pathogenesis, clinical presentation, diagnosis and management. Indian J Dermatol. 2015;60(3):222-229. doi:10.4103/0019-5154.156315.
Li C, Tang X, Zheng X, Ge S, Wen H, Lin X, et al. Global prevalence and incidence estimates of oral lichen planus: A systematic review and meta-analysis. JAMA Dermatol. 2020;156(2):172-181. doi:10.1001/jamadermatol.2019.3797.
Varghese SS, George GB, Sarojini SB, Vinod S, Mathew P, Mathew DG, et al. Epidemiology of oral lichen planus in a cohort of South Indian population: A retrospective study. J Cancer Prev. 2016;21(1):55-59. doi:10.15430/JCP.2016.21.1.55.
Omal PM, Jacob V, Prathap A, Thomas NG. Prevalence of oral, skin, and oral and skin lesions of lichen planus in patients visiting a dental school in Southern India. Indian J Dermatol. 2012;57(2):107-109. doi:10.4103/0019-5154.94276.
Bhonsle RB, Pindborg JJ, Gupta PC, Murti PR, Mehta FS. Incidence rate of oral lichen planus among Indian villagers. Acta Derm Venereol. 1979;59(3):255-257.
Nosratzehi T. Oral lichen planus: An overview of potential risk factors, biomarkers and treatments. Asian Pac J Cancer Prev. 2018;19(5):1161-1167. doi:10.22034/APJCP.2018.19.5.1161.
Sandhu SV, Sandhu JS, Bansal H, Dua V. Oral lichen planus and stress: An appraisal. Contemp Clin Dent. 2014;5(3):352-356. doi:10.4103/0976-237X.137946.
Mozaffari HR, Sharifi R, Sadeghi M. Prevalence of oral lichen planus in diabetes mellitus: A meta-analysis study. Acta Inform Med. 2016;24(6):390-393. doi:10.5455/aim.2016.24.390-393.
Alaizari NA, Al-Maweri SA, Al-Shamiri HM, Tarakji B, Shugaa-Addin B. Hepatitis C virus infections in oral lichen planus: A systematic review and meta-analysis. Aust Dent J. 2016;61(3):282-287. doi:10.1111/adj.12382.
González-Moles MÁ, Ruiz-Ávila I, González-Ruiz L, Ayén Á, Gil-Montoya JA, Ramos-García P. Malignant transformation risk of oral lichen planus: A systematic review and comprehensive meta-analysis. Oral Oncol. 2019;96:121-130. doi:10.1016/j.oraloncology.2019.07.012.
Axéll T, Rundquist L. Oral lichen planus—A demographic study. Community Dent Oral Epidemiol. 1987;15(1):52-56. doi:10.1111/j.1600-0528.1987.tb00480.x.
Xue JL, Fan MW, Wang SZ, Chen XM, Li Y, Wang L. A clinical study of 674 patients with oral lichen planus in China. J Oral Pathol Med. 2005;34(8):467-472. doi:10.1111/j.1600-0714.2005.00341.x.
Ingafou M, Leao JC, Porter SR, Scully C. Oral lichen planus: A retrospective study of 690 British patients. Oral Dis. 2006;12(5):463-468. doi:10.1111/j.1601-0825.2005.01221.x.
Munde AD, Karle RR, Wankhede PK, Shaikh SS, Kulkurni M. Demographic and clinical profile of oral lichen planus: A retrospective study. Contemp Clin Dent. 2013;4(2):181-185. doi:10.4103/0976-237X.114873.
Vallejo MJ, Huerta G, Cerero R, Seoane JM. Anxiety and depression as risk factors for oral lichen planus. Dermatology. 2001;203(4):303-307. doi:10.1159/000051777.
Mallah N, Ignacio Varela-Centelles P, Seoane-Romero J, Takkouche B. Diabetes mellitus and oral lichen planus: A systematic review and meta-analysis. Oral Dis. 2022;28(8):2100-2109. doi:10.1111/odi.13927.
Salgado DS, Jeremias F, Capela MV, Onofre MA, Massucato EM, Orrico SR. Plaque control improves the painful symptoms of oral lichen planus gingival lesions: A short-term study. J Oral Pathol Med. 2013;42(10):728-732. doi:10.1111/jop.12093.
Aghbari SMH, Abushouk AI, Attia A, Elmaraezy A, Menshawy A, Ahmed MS, et al. Malignant transformation of oral lichen planus and oral lichenoid lesions: A meta-analysis of 20,095 patient data. Oral Oncol. 2017;68:92-102. doi:10.1016/j.oraloncology.2017.03.012.
