Triple Antibiotic Paste: Boon to Dentistry
Keywords:
Endodontic treatment, TAP, AntibioticAbstract
Microorganisms must be removed from the root canal (RC) and periapical region for endodontic success. A sterile state cannot be achieved with only endodontic instrumentation. Local administration of antibiotics has been studied in light of the development of non instrumentation endodontic treatment, tissue healing and lesion sterilization. Triple antibiotic paste (TAP) with metronidazole, ciprofloxacin, and minocycline works well for non-vital young permanent teeth and the RC pathogen. Present review of literature aims to discuss role of TAP in endodontic treatment.
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References
1. Murray RR, Baron EJ, Pfaller MA, Tenover FC, Yolken RH. Manual of Clinical Microbiology. 7th ed. Washington, DC: ASM Press 1999. p. 264-82, 283-305.
2. Rocas IN, Siquera JF Jr, Aboim MC, Rosado AS. Denaturing gradient gel electrophoresis analysis of bacteria communities associated with failed endodontic treatment. Oral Surg Oral Med Oral Path Oral RadiolEndod 2004;98:741-9.
3. Kayaoglu G, Ørstavik D. Virulence factors of Enterococcus faecalis: Relationship to endodontic disease. Crit Rev Oral Biol Med 2004;15:308-20.
4. William W, 3rd, Teixeira F, Levin L, Sigurdsson A, Trope M. Disinfection of immature teeth with a TAP. J Endod 2005;31:439–43.
5. Makandar SD, Noorani TY. TAP––Challenging intracanal medicament: A systematic review. J Int Oral Health 2020;12:189-96.
6. Abbott PV. Selective and intelligent use of antibiotics in endodontics. Aust Endod J 2000;26(1):30–9.
7. Mohammadi Z, Jafarzadeh H, Shalavi S, Yaripour S, Sharifi F, Kinoshita JI. A Review on TAP as a Suitable Material Used in Regenerative Endodontics. Iran Endod J 2018;13(1):1-6. doi: 10.22037/iej.v13i1.17941. PMID: 29692827; PMCID: PMC5800433.
8. Malu K, Khubchandani M. TAP: A Suitable Medicament for Intracanal Disinfection. Cureus 2022;14(9):e29186. doi: 10.7759/cureus.29186. PMID: 36258984; PMCID: PMC9569130.
9. Rehan Haider. Penicillin and the Antibiotics Revolution Global History. Asian Journal of Pharmaceutical Research 2023;13(1):55-2. doi: 10.52711/2231- 5691.2023.00011
10. Hidayah Karuniawati, Mohamed Azmi Ahmad Hassali, Sri Suryawati, Wan Ismahanisa Ismail, Taufik Taufik, M Mutalazimah. Development and Validation of Knowledge, Attitude, and Practice Towards Antibiotics Questionnaire (KAPAQ) for General Community. Research Journal of Pharmacy and Technology 2022; 15(1):315-4. doi: 10.52711/0974-360X.2022.00052
11. Sangeetha Shankar, P. Gopinath, E. Roja. Role of Spices and Herbs in Controlling Dental Problems. Research Journal of Pharmacology and Pharmacodynamics 2022;14(1):23-8. doi: 10.52711/2321-5836.2022.00004
12. Ganesh G. Dhakad, Rohit V. Patil, Dhiraj S. Girase, Shraddha P. Amrutkar, Ritik S. Jain. Review on Antibiotics. Asian Journal of Research in Chemistry 2022; 15(1):91-6. doi: 10.52711/0974-4150.2022.00015
13. Deepak Prashar, Khushboo Jasra. Pharmacognostic, Phytochemical and Therapeutic Overview of three Allied Herbs used in Dentistry. Asian Journal of Research in Pharmaceutical Sciences 2021;11(2):121-5 doi: 10.52711/2231- 5659.2021-11-2-5
14. Parhizkar A, Nojehdehian H, Asgary S. TAP: momentous roles and applications in endodontics: a review. Restor Dent Endod 2018;20;43(3):e28. doi: 10.5395/rde.2018.43.e28. PMID: 30135847; PMCID: PMC6103545.
15. Prasannaand TD, Nilima T. Evaluation of a TAP as a RC Obturating Material for Deciduous Teeth: A Study Protocol. JPRI 2021:33(60B): 3909-3920.
16. Nair PNR, Sjögren U, Krey G, Kahnberg K-E, Sundqvist G. Intraradicular bacteria and fungi in root-filled, asymptomatic human teeth with therapy-resistant periapical lesions: A long-term light and electron microscopic follow-up study. J Endod 1990;16(12):580-588. DOI:10.1016/S0099-2399(07)80201-937.
17. Peters LB, van Winkelhoff A-J, Buijs JF, Wesselink PR. Effects of instrumentation, irrigation and dressing with calcium hydroxide on infection in pulpless teeth with periapical bone lesions. Int Endod J 2002;35(1):13-21. DOI:10.1046/j.0143-2885.2001.00447.x
18. Venkataraman M, Singhal S, Tikku AP, Chandra A. Comparative analysis of tooth discoloration induced by conventional and modified TAPs used in regenerative endodontics. Indian J Dent Res 2019;30:933-6.