Clinical Profile of Patients with Type 2 Diabetes Mellitus at a Tertiary Care Hospital
Keywords:
Diabetes mellitus, FBS, PPBSAbstract
Background: Diabetes mellitus is described as a group of metabolic disorders of multiple etiology characterized by chronic hyperglycemia associated with disturbances of carbohydrate, fat and protein metabolism due to absolute or relative deficiency of insulin secretion and/or action. Diabetes mellitus is associated with significant long term sequels, particularly damage or dysfunction of various organs especially kidneys, eyes, nerves, heart and blood vessels. Subjects and Methods: A pre-structured and pre-tested proforma was used to collect the data. Informed consent was taken from all cases and control subjects. Base line data including age and sex, detailed medical history including conventional risk factors, clinical examinations and relevant investigations were included as part of the methodology. Results: The mean serum FBS level among cases was 146.94±54.99 mg % as compared to 86.71±9.71 mg % among controls. There was highly significant difference in serum FBS levels among cases and controls. Conclusion: The mean serum PPBS level among cases was 244.26±96.47 mg % as compared to 111.96±8.85 mg % among controls. There was highly significant difference in serum PPBS levels among cases and controls.
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References
1. Suvarna J, Ingle H, Deshmukh CT, ―Insullin resistance and beta cell function in chronically trancfused patients of thalassemia major‖ Indian pedia 2006; 43: 393-400.
2. FaranakSharifi, N MousaviNasab, H JazebiZadeh,
2008.‖Elevated serum ferritin concentrations in prediabetic subjects‖. Diabetes Vascular diseasesRes.5 (1):15-18.
3. Hoskote S S, Joshi S R, ―Are Indians destined to be diabetic?‖ Journal of associations of physicians of India 2008, 56:225-226. 4. Kolterman DC, Gray RS. Griffin J. Receptor and post receptor defects contribute to the insulin resistance in NIDDM .J. ClinInrests 1981; 68;95.
5. Sumeet Smotra, VR Tandon, Sanjay Sharma, RP Kudyar, ―Serum ferritin and type 2 diabetes mellitus‖. Jk Science, 2007; 9(4): 164-166.
6. Felber JP, Ferrannini E, Golay A, Meyer HV, ―Role of lipid oxidation in pathogenesis of insulin resistance of obesity and
type 2 diabetes‖ Diabetes,1987 ; 36 : 1341-1350.
7. Hunt JV, Smith CL, Wolf SP, ―Auto oxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose‖. Diabetes, 1990 ; 39 :1420-1424.
8. Halliwell B, Gutteridge JM, ―Role of free radicles and catalytic metal ions in human disease ; an over view‖. Methods enzymol 1990 : 186 : 1-85.
9. Sullivan JL, ―Iron and the sex difference in heart disease risk‖. Lancet 1, 1981 ; 1293-1294.
10. Salonen JT, Nyyssnen K, Salonen R, ―Body iron stores and the risk of coronary heart disease‖. N Engl J Med, 1994 ; 331 : 1159 (letter).