Study of Serum Lipid Profile in Type-2 Diabetes Mellitus Patients
Keywords:
Serum Lipid Profile, Type-2 Diabetes Mellitus, DyslipidemiaAbstract
Background: Dyslipidemia may cause or exacerbate diabetic retinopathy and nephropathy and alterations in the coagulation-fibrnolytic system, changes in membrane permeability, damage to endothelial cells and increased atherosclerosis.Serum triglycerides and all types of lipoproteins are affected and this leads to increase morbidity and mortality in type 2 diabetic patients. Subjects and Methods: A total of 100 with type-2 diabetes mellitus irrespective of duration of diabetes in the age group of 35-80 years formed the study subjects. A pre-structural proforma will be used to collect baseline date detailed clinical history with clinical examination and relevant investigation will be done on participating individuals. Results: During our study we randomly selected 100 Diabetes mellitus-type-2 patients visiting OPD or admitted in the department of Medicine at our institution. Out of 100 DM patients, 61 were Males and 39 were Females. The Mean age of patients in our study was 57.29 +56.55 mg/dl and mean PPBS was 252 +73.76 mg/dl. Conclusion: This study shows significant increasing levels of TG, TC, LDl-C, and Vdl-C and significant decrease in level of HDL-C has the severity of diabetes.
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References
1. Punyakrit Deb Barma, Salam Ranabir, Lallan Prasad, and thanglamPremachandsingh, clinical and biochemical profile of lean type 2 diabetes mellitus. Indian J endocrinolMetab. 2011; 15 (5): 40-3.
2. Agrawal RP, Sharma P, Pal M., Kochar A, Kochar DK. Magnitude of dyslipidemia and its association with mocro and macro vascular complications in type 2 diabetes: A hospital based study from Bikaner. Diabetes Res Clinpract 2006; 73(2):211-4.
3. Mistra A, Kumar S, Kishore Vikram N, Kumar A. The role of lipids in the developemtn of diabetic
4. Amin-U1-Haq, et al. Pattern of Lipid Profile in type 2 diabetes mellitus patients. JPMI 2006;20(4)”366-9
5. Jisieike- Onuigbo NN, Unuigbe EI, Oguejiofor CO. Dyslipidemias in ype 2 diabetes mellitus patients in Nnewi south-East Nigeria. Ann Afr Ned, 2011; 10(4);285-9. microvascular complications implications for therapy. Am J Cardiovase: Drugs. 2003;3(5):325-38.
6. Chehade JM, Gladysz M, Mooradian AD. Dyslipidemia in type 2 diabetes: prevalence, pathophysiology, and management, Drugs. 2013;73(4):327-39.
7. Zoppini G, negri c, Stoico V, Casati S, Pichiri I, Bonora E. Triglyceride-high-density lipoprotein cholesterol in associated with microvascular complications in type 2 diabetes mellitus. Metabolism 2012:61(1):22-9.
8. Mahato RV, Gyawali P, Raut PP, Regmi P, Khelanand Ps, Dipendra RP, Gyawali P. Association between glycaemic control and serum lipid profile in type 2 diabetc patients: glycatedhaemoglobin as a dual biomarker. Biomed Res. 20111;22(3);375-380.15.
